Version list

NOTE: this website is frozen since May 1, 2016. It has been replaced by a new version at http://www.HGVS.org/varnomen. These pages serve as archival copy only.

This page lists the latest changes in the HGVS recommendations for the description of sequence changes and shows the latest version number. For details, see Versioning.

New versions

• Version 2.1511
  Accepted proposals include SVD-WG001 and SVD-WG002
  SVD-WG001 (No change) allows descriptions like g.11890634G=, c.123G=, r.123g= and p.(Arg41=).
  SVD-WG001 (n. reference sequence) allows descriptions like NR_028379.1(FTX):n.345A>G.
  
• Version 2.121101
  Variants affecting translation termination  -  at protein level, variants that replace the translation termination codon but do not encounter a new stop codon in the new reading frame are described using the format "p.*321Argext*?", frame shift variants with the same effect are described using the format "p.Ile321Argfs*?" (see Protein descriptions)
• Version 2.120831
  • Protein description between brackets  -  brackets can be omitted when there is sufficient experimental proof from other studies.
  • Variants affecting translation initiation  -  at protein level, variants that generate a new upstream translation initiation codons are described using the format "p.Met1ext-5" (see Discussion).

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